----------------------------------------------------------------------------------------------------------------------------------- Safety, pharmacokinetics, and antiviral activity of the capsid inhibitor AB-506 from Phase 1 studies in healthy subjects and those with hepatitis B |
Yuen Man-Fung1, Berliba Elina2, Sukeepaisarnjaroen Wattana3, Ahn Sang Hoon4, Tanwandee Tawesak5, Lim Young-Suk6, Kim Yoon Jun7, Poovorawan Kittiyod5, Tangkijvanich Pisit8, Schwabe Christian9, Eley Timothy10, Brown Joanne10, Noi Autori1, Gane Edward John11 |
1 University of Hong Kong, Hong Kong, 4 Yonsei University, Seoul, 5 Mahidol University, Bangkok, 6 Asan Medical Center, Seoul, 7 Seoul National University, 9 Auckland Clinical Studies, Auckland, 10 Arbutus Biopharma, Warminster, 11 University of Auckland |
Hepatology Communications |
Nr. / 2022 / ISSN 2471-254X |
Disponibil online 12 September, 2023. Descarcări-4. Vizualizări-232 |
----------------------------------------------------------------------------------------------------------------------------------- HBsAg isoform dynamics during NAP-based therapy of HBeAg-negative chronic HBV and HBV/HDV infection |
Bazinet Michel1, Anderson Mark2, Pântea Victor3, Plăcintă Gheorghe3, Moscalu Iurie4, Cebotarescu Valentin3, Cojuhari Lilia3, Jimbei Paulina5, Iarovoi Liviu3, Smeşnoi Valentina5, Musteaţă Tatiana5, Jucov Alina34, Dittmer Ulf6, Gersch Jeffrey2, Holzmayer Vera2, Kuhns Mary C.2, Cloherty Gavin A.2, Vaillant Andrew1 |
2 Abbott Diagnostics, Abbott Park, IL, 3 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 5 Toma Ciorba Clinical Hospital of Infectious Diseases, 6 Duisburg - Essen University |
Hepatology Communications |
Nr. / 2022 / ISSN 2471-254X |
Disponibil online 11 September, 2023. Descarcări-0. Vizualizări-170 |
----------------------------------------------------------------------------------------------------------------------------------- Analysis of HBsAg Immunocomplexes and cccDNA Activity During and Persisting After NAP-Based Therapy |
Bazinet Michel1, Anderson Mark2, Pântea Victor3, Plăcintă Gheorghe3, Moscalu Iurie4, Cebotarescu Valentin3, Cojuhari Lilia3, Jimbei Paulina5, Iarovoi Liviu3, Smeşnoi Valentina5, Musteaţă Tatiana5, Jucov Alina4, Dittmer Ulf6, Gersch Jeffrey2, Holzmayer Vera2, Kuhns Mary C.2, Cloherty Gavin A.2, Vaillant Andrew1 |
2 Abbott Diagnostics, Abbott Park, IL, 3 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 5 Toma Ciorba Clinical Hospital of Infectious Diseases, 6 Duisburg - Essen University |
Hepatology Communications |
Nr. / 2021 / ISSN 2471-254X |
Disponibil online 12 September, 2023. Descarcări-2. Vizualizări-169 |
----------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------- Reaction of 6-Methyl-2-Thiouracil and 6-Phenyl-2-Thiouracil with Chloro-β-Dicarbonyl and Bromo-β-Dicarbonyl Compounds and Their Nitrile Analogs |
Iavolovskii A1, Ivanov Iu.1, Fonari Marina2, Croitor Lilia2, Grishchuk L.1, Ivanova R.3, Camalov Gherbert1 |
1 A.V. Bogatsky Physico-Chemical Institute of the NAS of Ukraine, 2 Institute of Applied Physics, Academy of Sciences of Moldova, 3 Odessa National Maritime University |
Journal of Heterocyclic Chemistry |
Nr. 6(53) / 2016 / ISSN 0022-152X |
Disponibil online 26 January, 2023. Descarcări-0. Vizualizări-250 |
----------------------------------------------------------------------------------------------------------------------------------- Marine Terpenoid Diacylguanidines: Structure, Synthesis, and Biological Evaluation of Naturally Occurring Actinofide and Synthetic Analogues |
Carbone Marianna1, Ciavatta Maria-Letizia1, Mathieu Veronique2, Ingels Aude2, Kiss Robert2, Pascale Paola1, Mollo Ernesto1, Ungur Nicon3, Guo Yuewei4, Gavagnin Margherita1 |
2 Free University of Brussels, 3 Institute of Chemistry of the Academy of Sciences of Moldova,
|
Journal of Natural Products |
Nr. / 2017 / ISSN 0163-3864 /ISSNe 1520-6025 |
Disponibil online 21 February, 2018. Descarcări-0. Vizualizări-912 |
----------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------- ----------------------------------------------------------------------------------------------------------------------------------- Safety and efficacy of REP 2139 and pegylated interferon alfa-2a for treatment-naive patients with chronic hepatitis B virus and hepatitis D virus co-infection (REP 301 and REP 301-LTF): a non-randomised, open-label, phase 2 trial |
Bazinet Michel1, Pântea Victor2, Cebotarescu Valentin2, Cojuhari Lilia2, Jimbei Paulina3, Albrecht Jeff A4, Schmid Peter4, Le Gal Frederic5, Gordien Emmanuel5, Krawczyk Adalbert6, Mijocevic Hrvoje7, Karimzadeh Hadi7, Roggendorf Michael7, Vaillant Andrew1 |
2 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 3 Toma Ciorba Clinical Hospital of Infectious Diseases, 6 Duisburg - Essen University,
|
The Lancet Gastroenterology and Hepatology |
Nr. / 2017 / ISSN 2468-1253 |
Disponibil online 11 December, 2017. Descarcări-1. Vizualizări-871 |
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