This work presents the results of investigations in the frame state testing the products for phytosanitary use Lab 05-F, SC, Lab 06–F, SE, Duo SCC, Virtuoz EC, Mirage 45 EC as fungicides on autumn cereals crops during the period of vegetation of 2017-2018 years. It was established the ethyological component, grade of intensity and the frequency of the phytopathogenic agents in the period of vegetation at autumn wheat and barley as they are: Erysiphe graminis f. sp. tritici, s.p. hordei, Puccinia anomala, Puccinia recondita, Helminthosporium gramineum, Helminthosporium tritici-repentiss Helminthosporium teres, Septoria graminum, Septoria nodorum anomala, Fusarium graminearum. On the base of the experimental results obtained the preparations tested had a high biological effiency in the combat of leaf diseases at autumn cereals in critical phases of the periods of vegetation. have been included in the integrate protection system.