The scientific article includes the analysis of two blocks of issues: the content of the Declaration of Independence of the Republic of Moldova addressed by elucidating domestic and foreign policy objectives: defining the national interest of the Republic of Moldova and detailed research of a component - ensuring the territorial integrity of Moldova sovereignty over its entire territory. The main idea is that the Declaration of Independence was written in the spirit of historical optimism and aspirations for a better life. In reality, however, the results did not confirm the expectations, the national interest is not assumed by legislative acts and the social energies are not coagulated for its realization. The Republic of Moldova is a vulnerable state, and the realization of the European vocation of its people, as well as other components of the national interest, continues to be on the agenda of the day, because time passes.