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Ultima descărcare din IBN: 2023-04-28 21:45 |
SM ISO690:2012 TOFAN-SCUTARU, Liudmila, CERVINSKI, Irina, DUMBRAVA, Vlada-Tatiana, LUPAŞCO, Iulianna, TARAN, Natalia, BERLIBA, Elina, ŢURCAN, Svetlana, PROCA, Nicolae, MOSCALU, Iurie, ŢURCANU, Adela, COBÎLTEAN, Lucia, CHIRVAS, Elena, HAREA, Gheorghe, COJUHARI, Maria, GANEA, Cătălin. Manifestările clinico-paraclinice și factorii precipitanți ai insufi cienței hepatice cronice din ciroza hepatică. In: Sănătate Publică, Economie şi Management în Medicină , 2013, nr. 5(50), pp. 165-173. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | |||
Numărul 5(50) / 2013 / ISSN 1729-8687 /ISSNe 2587-3873 | |||
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Pag. 165-173 | |||
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The study group included 80 patients with liver cirrhosis (LC), Child-Pugh stage B and C average age 54.95 ± 1.09 years, with chronic liver failure (CLF). Lot of comparison – and 21 patients with liver cirrhosis, Child-Pugh stage A. Clinical manifestations in patients with liver cirrhosis Child-Pugh stage B and C with chronic liver failure, shows polymorphism; there were found basic clinical syndromes: ascites (91.3%), jaundice (88.7%), bleeding (53.8%), fever (47.5%), endocrine (9%), of cardiovascular disorders (30%). We established the base of the CLF precipitating factors: alcohol (45%), spontaneous bacterial peritonitis (23.8%), respiratory infections and / or urinary infections (18.8%), upper gastrointestinal bleeding (20%) misuse of food proteins (20%). Reliable correlations were determined between respiratory infections and / or urinary infections with Child-Pugh score and MELD score. We determined the presence of multiple precipitating factors and also established correlation between the values MELD score with number precipitating factors of CLF from LC. In patients with LC with CLF it was established true positive correlation of the hepatodepressive syndrome indices studied each and with serum Na+ and negative correlation with the degree of ascites and with Child-Pugh and MELD scores. It was established truthful negative correlation of natriemi with total bilirubin and MELD and Child-Pugh scores, so hyponatremia may serve as a prognostic factor for the development of CLF from LC. |
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Cuvinte-cheie Chronic liver failure, cirrhosis, Child-Pugh, MELD, хроническая печеночная недостаточность, цирроз печени, Child-Pugh, MELD |
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Cerif XML Export
<?xml version='1.0' encoding='utf-8'?> <CERIF xmlns='urn:xmlns:org:eurocris:cerif-1.5-1' xsi:schemaLocation='urn:xmlns:org:eurocris:cerif-1.5-1 http://www.eurocris.org/Uploads/Web%20pages/CERIF-1.5/CERIF_1.5_1.xsd' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' release='1.5' date='2012-10-07' sourceDatabase='Output Profile'> <cfResPubl> <cfResPublId>ibn-ResPubl-95437</cfResPublId> <cfResPublDate>2013-10-01</cfResPublDate> <cfVol>50</cfVol> <cfIssue>5</cfIssue> <cfStartPage>165</cfStartPage> <cfISSN>1729-8687</cfISSN> <cfURI>https://ibn.idsi.md/ro/vizualizare_articol/95437</cfURI> <cfTitle cfLangCode='RO' cfTrans='o'>Manifestările clinico-paraclinice și factorii precipitanți ai insufi cienței hepatice cronice din ciroza hepatică</cfTitle> <cfKeyw cfLangCode='RO' cfTrans='o'>Chronic liver failure; cirrhosis; Child-Pugh; MELD; хроническая печеночная недостаточность; цирроз печени; Child-Pugh; MELD</cfKeyw> <cfAbstr cfLangCode='EN' cfTrans='o'><p>The study group included 80 patients with liver cirrhosis (LC), Child-Pugh stage B and C average age 54.95 ± 1.09 years, with chronic liver failure (CLF). Lot of comparison – and 21 patients with liver cirrhosis, Child-Pugh stage A. Clinical manifestations in patients with liver cirrhosis Child-Pugh stage B and C with chronic liver failure, shows polymorphism; there were found basic clinical syndromes: ascites (91.3%), jaundice (88.7%), bleeding (53.8%), fever (47.5%), endocrine (9%), of cardiovascular disorders (30%). We established the base of the CLF precipitating factors: alcohol (45%), spontaneous bacterial peritonitis (23.8%), respiratory infections and / or urinary infections (18.8%), upper gastrointestinal bleeding (20%) misuse of food proteins (20%). Reliable correlations were determined between respiratory infections and / or urinary infections with Child-Pugh score and MELD score. We determined the presence of multiple precipitating factors and also established correlation between the values MELD score with number precipitating factors of CLF from LC. In patients with LC with CLF it was established true positive correlation of the hepatodepressive syndrome indices studied each and with serum Na+ and negative correlation with the degree of ascites and with Child-Pugh and MELD scores. It was established truthful negative correlation of natriemi with total bilirubin and MELD and Child-Pugh scores, so hyponatremia may serve as a prognostic factor for the development of CLF from LC.</p></cfAbstr> <cfAbstr cfLangCode='RU' cfTrans='o'><p>В основной группе включены 80 пациентов с циррозом печени (ЦП), стадии Child-Pugh В или С, средний возраст 54,95±1,09 лет, с хронической печеночной недостаточностью (ХПН). Группа сравнения – 21 больных с ЦП, стадия Child-Pugh А. Клинические проявления у пациентов с ЦП стадии Child-Pugh B или C, с ХПН показывают полиморфизм; установлены основные клинические синдромы: асцитический (91,3%), желтушный (88,7%), геморагический (53,8%), лихорадки (47,5%), эндокринный (9%), сердечно-сосудистых нарушений (30%). Определены основные провоцирующие факторы ХПН: алкоголь (45%), спонтанный бактериальный перитонит (23,8%), инфекции дыхательных и/ или мочевыводящих путей (18,8%), кровотечения из варикозно-расширенных вен пишевода и желудка (20%), богатая белком диета (20%). Установлена корреляция инфекций дыхательных и/или мочевыводящих путей с баллами оценки ЦП по шкале Child-Pugh и по MELD. Чаще встречалось сочетание нескольких триггерных факторов ХПН. Обнаружена корреляция оценки ЦП по MELD с количеством обнаруженных сопутствующих провоцирующих факторов ХПН. У пациентов с ЦП с ХПН выявлена положительная корреляция исследованных показателей гепатодепрессивного синдрома с Na+ в сыворотке и отрицательная корреляция со степенью асцита и с баллами оценки ЦП по шкале Child-Pugh и по MELD. 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