|Conţinutul numărului revistei|
|Ultima descărcare din IBN:|
| SM ISO690:2012|
KINTIA, Pavel; SHVETS, Stepan; FAVEL, Anna; PIZZA, Cosimo. Steroidal glycosides from the seeds of hyoscyamus niger L. and their antifungal activity. In: Chemistry Journal of Moldova. 2007, nr. 1(2), pp. 108-113. ISSN 1857-1727.
|Chemistry Journal of Moldova|
|Numărul 1(2) / 2007 / ISSN 1857-1727 /ISSNe 2345-1688|
Phytochemical analysis of the seeds of Hyocyamus niger L. (Solonaceae) resulted in the isolation of six steroidal glycosides, two furostanol (1, 2) and four spirostanol saponins (3, 4, 5, 6), which were found in this plant for the ﬁrst time. The structures of these compounds were determined by detailed analysis of their spectral data, including two-dimensional NMR spectroscopy and MS spectroscopy. The antifungal activity of a crude steroidal glycoside extract, fractions of spirostanoles and individual glicosides was investigated in vitro against a panel of human pathogenic fungi, yeasts as well as dermatophytes and ﬁlamentous species.
Hyoscyamus niger L., steroidal glycosides,