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 1249 6 |
| Ultima descărcare din IBN: 2023-08-07 10:59 |
 SM ISO690:2012TODIRAŞ, Mihail, RUDIK, V., PARII, Sergiu, GUDUMAK, V., RUSNAC, Liliana, GOLOVIN, Pavel, CHIRIAC, Tatiana, VALICA, Vladimir. Neamon-Hepa on Carbon Tetrachloride-Induced Hepatotoxicity: Antioxidant Properties. In: Curierul Medical, 2010, nr. 4(316), pp. 3-6. ISSN 1875-0666. |
| EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
| Curierul Medical | ||||||
| Numărul 4(316) / 2010 / ISSN 1875-0666 | ||||||
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The present study was undertaken to investigate whether Neamon-Hepa treatment provides antioxidant protection from chronic liver
injury induced in mice by a long-term CCl4 administration. The Neamon-Hepa capsule, a combination indigene drug, contains L-arginine,
Spironolactone and biopreparation from the Spirulina platensis - BioR. Carbon tetrachloride chronic treatment for three weeks significantly
decreased the hepatic antioxidant enzyme activities - almost twofold superoxide dismutase enzyme activity, catalase activity, glutathione peroxidase
activity in liver tissue and induced a marked elevation almost twofold of thiobarbituric acid reactive substances levels in the plasma and liver
tissue. Treatment with the Neamon-Hepa following experimental liver damage, in a dose-dependent way, resulted in a marked augmentation
of antioxidant enzyme activities and reduction of lipid peroxidation levels. |
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| Cuvinte-cheie Neamon-Hepa, antioxidant properties, induced hepatotoxicity |
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