The process of European integration of Republic of Moldova even it is characterized by an accelerated tempo, encount great difficulties regarding the adjustment of legislation, norms and general values to european community. Theorists of international relations in their works of reference, define integration in different ways, based on events that took place and geopolitical area. Theoretical and methodological indicators of European integration and the practical implementation of the process of national interest of states that want to go through were articulated around different schools and currents, among the most representative we consider to be (neo)realism, (neo)liberalism, social constructivism, intergovernmentalism, (neo) liberal functionalism, confederalism.