Currently with particular attention of small and medium enterprises, whose existence in the economic structure of a country is absolutely indispensable. We know that they always represent a special role in economic and social life of society, being out in the revival of many economies. With the emergence and assertion of small and medium business in economies that are in the process of developing a new phenomenon and a central component of any program of economic reform, accepting a global perspective on the phenomenon, represents an essential condition to achieve a relevant research. A central point of departure in research problems of small and medium enterprises presents how they are defined, comparing definitions, the role of this type of business and health policies in different countries and that type of business impact analysis macroeconomic structure. The fundamental purpose of this research is focused on the development of contributions to the foundation of small and middle business in the context of integration into the European Union.