Venous sinus thrombosis in children: diagnostic approach, evolution
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HADJIU, Svetlana, CALCII, Cornelia, MARGA, Simion, FEGHIU, Ludmila, LUPUŞOR, Nadejda, GRÎU, Corina, CUZNETZ, Ludmila, ISTRATIUC, Irina, CAPESTRU, Elena, CALISTRU, Iulia, CONSTANTIN, Olga, SPRINCEAN, Mariana, REVENCO, Ninel. Venous sinus thrombosis in children: diagnostic approach, evolution. In: Revista de Neurologie si Psihiatrie a Copilului si Adolescentului din Romania, 2023, vol. 29, nr. 3(R), pp. 19-20. ISSN 2068-8040.
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Revista de Neurologie si Psihiatrie a Copilului si Adolescentului din Romania
Volumul 29, Numărul 3(R) / 2023 / ISSN 2068-8040

Venous sinus thrombosis in children: diagnostic approach, evolution


Pag. 19-20

Hadjiu Svetlana12, Calcii Cornelia12, Marga Simion12, Feghiu Ludmila13, Lupuşor Nadejda12, Grîu Corina12, Cuznetz Ludmila12, Istratiuc Irina12, Capestru Elena12, Calistru Iulia12, Constantin Olga12, Sprincean Mariana12, Revenco Ninel12
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Institute of Mother and Child,
3 National Epileptology Center of the Republic of Moldova
 
 
Disponibil în IBN: 24 martie 2024


Rezumat

Introduction. Cerebral venous sinus thrombosis (CVST) is a severe pathology that rarely occurs in children. Thanks to advances in neuroimaging in recent years, the degree of recognition of this disease has increased. The aim of the study is to analyze the etiological and clinical-imaging characteristics of CVST in children to improve the diagnosis of this disease. Material and methods. A retrospective study was carried out on the cases of children with CVST in the pediatric neurology clinic of the Department of Pediatrics within the IMSP IMC in the Republic of Moldova (year 2015 – 2021). Instruments: CT and/or MRI of the brain. Statistical method: t-student test. Results: 19 children were enrolled in the study (f – 7 / 37%, b – 12 / 63%). The average age of the studied children was calculated – 4.08 years (age range 0.13-14 years). The most common presenting symptoms initially: hyperexcitability – 11 (57.9%), convulsions – 10 (52.6%), headache – 9 (47.4%), nausea – 8 (42%), vomiting – 7 (36.8%), vertigo – 6 (31.6), fever – 6 (31.6%), motor disturbances – 6 (31.6%) and visual disturbances – 4 (21%) cases. Imaging examinations allowed the sinus occluded by thrombus to be highlighted. Thus, the superior sagittal sinus was one of the most frequent sites of occlusion – 11 (57.9%) cases, followed by the transverse sinus – 8 (42.1%) patients. In part of the patients (47.4%), multiple involvement of the sinuses was observed. In most children, concurrent pathologies were detected - 17 (89.5%), in 2 (10.5) cases the cause was not found. Risk factors associated with CVST were CNS infections – 8 (42%) cases, head trauma – 4 (21%), iron deficiency anemia – 2 (10.5%), inherited thrombophilia – 1 (5%), dehydration – 1 (5%), arteriovenous malformation – 1 (5%) child. In evolution, 5 (26.3%) of the children had a good neurological result, 13 (68.4%) presented motor disorders, 4 (21%) – visual disorders, 1 (5%) child died. Conclusions: Advances in neuroimaging in recent years have improved the degree of recognition of CVST. Among the most common causes are the child’s neuroinfections, followed by head trauma. CVST is associated with significant neurological morbidity in children. 

Cuvinte-cheie
child, cerebral venous sinus thrombosis (CVST), imaging