The financial and economic global system was changed due to the world economic financial crisis that affected most of the countries. Crisis is a process of transformation where the old system can no longer be maintained. Therefore, the cause of a crisis is the need for change. A solution for the actual financial crisis can be the knowledge economy. But knowledge has no resilience. If we fear for the security of the supply chains for food and energy, how much more should we be nervous about our knowledge? Not only is it floating free of any relationship with the real world, it is also stored on highly transient media. The research- development-innovation activity could bring a solution for the ending of the crisis and developing the knowledge economy that will save the economy.