Introduction. Decompensated liver disease (DLD), liver chirrosis (LC) is the most prevalent condition that can develop sarcopenia, a strong prognostic/predictor of patients’ mortality. The aim was to highlight the new aspects regarding the sarcopenic syndrome (SS) through a current approach to the diagnosis and management in LC. Material and methods. A contemporary literature analysis focused on the main databases was performed, 40 bibliographic sources were reviewed: PubMed, Hinari, SpringerLink and Scopus. The key word used was Sarcopenia. Inclusion criteria served clinical practice guidelines, scientific articles: pathophysiology, management and medical treatment of sarcopenia. Exclusion criteria were articles that did not meet the current requirements and information provided for patients. Results. DLD is characterized by muscle wasting, malnutrition and functional decline, while 17-43% of patients develop frailty. Frail versus non-frail patients have higher MELD scores, lower sodium and albumin levels. Sarcopenia is associated with a high degree of systemic inflammation, reported by the increase of pro-inflammatory cytokines, the development of oxidative stress, mitochondrial dysfunction, manifesting the basic role in sarcopenia pathogenesis. The SS pathogenesis involves 3 main causes: inadequate dietary intake, metabolic disturbances and malabsorption. Pretesting patients with frailty measurements demonstrated improved predictability and decreased mortality. Conclusions. Management of sarcopenia requires tailored to the individual requirements and specifics, focusing on high protein intake, regular meals, physical exercise, treatment of the liver disease.