Ecological security presents a complex, multidimensional phenomena. Ecological security analysis is important and useful in decision-making, developing measures in environmental management and maintaining sustainable ecological development. From here it becomes possible to classify it based on different criteria, thus establishing its main types. In this paper, an analysis of ecological security based on the PSR (Pressure-State-Response), model is attempted, for the territory of the Republic of Moldova, in which to highlight the strong influence of human activities that caused strong damage to the original structure of the landscape, leading to ecosystem imbalance. The PSR model is widely used in ecological research and reflects the causal relationship between human activities and the natural environment. Being an adaptable and feasible model, it encompasses all categories of risk, providing a good reference for establishing the ecological security evaluation index system.