Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
315 15 |
Ultima descărcare din IBN: 2024-04-24 05:58 |
Căutarea după subiecte similare conform CZU |
547.7:615.2 (1) |
Chimie organică (484) |
Medicamentele potrivit acţiunii lor principale (395) |
SM ISO690:2012 POPUSHOI, Ana. Study of the synthesis methods of 1,3-aryl(heteryl)propenone. In: Studia Universitatis Moldaviae (Seria Ştiinţe Reale şi ale Naturii), 2022, nr. 6(156), pp. 159-171. ISSN 1814-3237. DOI: https://doi.org/10.5281/zenodo.7445813 |
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Studia Universitatis Moldaviae (Seria Ştiinţe Reale şi ale Naturii) | ||||||
Numărul 6(156) / 2022 / ISSN 1814-3237 /ISSNe 1857-498X | ||||||
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DOI:https://doi.org/10.5281/zenodo.7445813 | ||||||
CZU: 547.7:615.2 | ||||||
Pag. 159-171 | ||||||
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In this work, we refer to the study of recent specialized literature, where some syntheses methods of chalcone derivatives are described. These substances show a very pronounced anticancer activity, having a protective action in the cellular system. They present interest due to their biological properties, such as anti-inflammatory, antioxidant, cytotoxic and antihistamine properties, etc. These important biological properties are the basis of the current research intended to obtain them synthetically. The bibliographic data refers to the synthesis of 1,3-aryl (heteryl) propenones, which are described in several reviews. The main focus is on the synthesis methods of chalcones, which allow us to obtain pure reaction products, short reaction time and high yields. Also, synthesis methods with the use of solid-based heterogeneous catalysts are described, which, in turn, are very active, durable and more economical and can be used for three synthesis cycles, without significant loss of catalytic activity. The synthesis methods studied were: aldol and crotonic condensation, Claisen-Schmidt reaction, Suzuki reaction, coupling of alkynes with aldehydes, microwave irradiation, etc. |
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Cuvinte-cheie chalconnes, condensation Claisen-Schmidt, synthesis, synthetic, Chalcone, condensare Claisen-Schmidt, sinteză, sintetic |
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