This the research study has been achieved aiming to determine the concentration of heavy metals in the berries juice of vines of the distant hybrids Vitis vinifera L. x Muscadinia rotundifolia Michx. compared to some varieties of the culture vines. The obtained results proves that berries juice of the hybrids distant of vines, hold heavy metals: Fe, Cu, Zn, Pb, Cd, As and Hg within limits lower than those accepted by the World Organisation of Vine and Wine. The concentration of heavy metals Fe, Cu, Zn, Pb, Cd, As and Hg from the juice of grapes of vines of distance hybrids (Vitis vinifera L. x Muscadinia rotundifolia Michx.) Is much lower than the maximum allowable limits approved by the World Vine and Wine (OMVV). The quality of the products derived of vegetable origin is conditional upon a number of factors: the quality of the substrate on which the develops the plants used in irrigation aquatic resources, atmospheric air, the techniques for combating diseases and pests etc.