The article analyzes the political realities in the context of COVID-19 pandemics offering prognoses for the future parliamentary elections as well as the interpretation of the existing expectations of the election results provided by the major political actors in the Republic of Moldova including political leaders of parties, analytical companies and other institutions. It also, presents an assessment of COVID-19 crisis management by the changing governments in the country by highlighting the current situation of the sanitary crisis. The methodology of the paper is based on data analysis methods of exact prognoses and factological synthesis of the domestic and external political relations between political parties and opposition, foreign intervention and simple people’s needs.