Astaxanthin, a pigment of the carotenoid group, is one of the most valuable antioxidants currently known. Among the few biological objects that perform the synthesis of astaxanthin, green microalga Haematococcus pluvialis is considered one of the most valuable producer of this pigment. The maximum amount of astaxanthin is accumulated in the nonmotile aplanospore stage of this alga, when the cellular structure is characterized by the presence of a rigid wall, which creates a serious obstacle to pigment extraction. The selection of an efficient method of cell wall destruction to facilitate the extraction of astaxanthin constitutes a crucial moment for potential commercial use of pigment. Selected methods should be harmoniously included in the techniques of subsequent food or pharmaceutical processing of astaxanthin. For this purpose, there have been tested some techniques applied for preliminary treatment of H. pluvialis red cysts as raw material with direct extraction of astaxanthin from biomass and its solubilization in vegetable oil. There have been conducted researches to determine the degree of solubilization of astaxanthin in vegetable oil. Two techniques were used in the pretreatment of cysts 1) acid hydrolysis with 0.1N HCl and 2) application of microwaves. It was applied the microwave regime of 540W for 120 sec. By applying this microwave regime on H. pluvialis biomass, astaxanthin extractability in alcohol was 84% and 82% in acetone. Sunflower and olive oils were used as solvents. The degree of solubilization of astaxanthin was expressed in % of astaxanthin present in biomass subjected to extraction. In order to obtain the oily product with astaxanthin, the process of direct extraction, by shaking, of the astaxanthin in oil was applied during 60 min, 3, 24 and 48 hours.After 60 min contact of the oil with red cysts, pretreated by acid hydrolysis, in sunflower oil passed 71% astaxanthin and 64% in olive oil; after 180 min, both sunflower oil and olive oil already contained 90-91% astaxanthin from the content proposed for solubilization. The extraction time of 24 and 48 hours maintained the solubilization of astaxanthin at the level of 90-95%. Thus, the maximum extraction time of astaxanthin was 24 hours, but in terms of technological reasoning, the extraction time of 3 hours was more convenient, when acid hydrolysis was applied as a pretreatment technique. In the case of pretreatment of cysts with microwaves of 540W power level, after 60 min contact of the oil with red cysts, in sunflower oil passed 88% astaxanthin, and in olive oil – 95%. During 180 min in both types of oil the content of astaxanthin was 91-95%. Therefore, the maximum extraction time of astaxanthin and technologically optimal time was 60 min under the conditions of applying the pretreatment microwave technique of aplanospores.  The introduction of microwave treatment technique of Haematococcus pluvialis biomass, as a stage of pretreatment of aplanospores, in the process of direct extraction of astaxanthin into vegetable oils reduced the solubilization time of pigment by three times.