Discrete compounds of Co(II) and Cu(II), incorporating ligands with different sets of donor atoms, remain attractive for research because of its usefulness and relevantce, such as biological activity, theoretical studies, magnetic properties, catalysis, etc. [1]. Monopyridyl ketones, such as 2benzoylpyridine (2-bzpy), are potentially bidentate ligands which may show interesting coordination properties towards metal ions. With an acyl substituent at the 2-position on the pyridine ring, several possibilities arise regarding the mode of interaction between the ligands and the metal ions: the carbonyl oxygen may coordinate along with the nitrogen of the pyridine ring on the central metal ion to form a five-membered chelate ring, or the nitrogen atom may function alone as a monodentate ligand. Thus, the combination of Co(II) and Cu(II) salts with 2-bzpy resulted in two coordination mononuclear compounds [Co(bzpy)2(H2O)2][BF4]2 (1) and [Cu(2-bzpy)2Cl2] (2) (Figure). The X-ray study established that compound 2 has been shown to be a polymorph of the dichloro-bis(2-benzoylpyridin-2-yl-N,O)-copper(II) (2)' [2], different by crystal systems, unit cells and geometric parameters.   1 2  Compound 1 crystallizes in centrosymmetric monoclinic space group P21/n: a = 9.0790(5), b = 11.6909(5), c = 12.8702(5) Å; β = 92.493(5)°. The Co(II) ion displays a distorted N2O4 octahedral coordination involving two N and two O atoms of two 2-bzpy ligands and two O atoms of two water molecules coordinated in axial position. Crystal packing reveals that the hydrophilic outer sphere [BF4]- anions are interconnected through the O–H···F hydrogen bonds with coordinated water molecules in 2D supramolecular layer, that further are interconnected via weak π-π stacking interactions between 2-bzpy ligands of neighboring parallel layers, yielding 3D supramolecular network. Compound 2 crystallizes in centrosymmetric triclinic space group P-1: a = 7.3015(7), b = 8.2013(8), c = 10.8395(11) Å, α = 107.777(9), β = 95.380(8), γ = 113.191(9) °. The compound 2' crystallizes in the centrosymmetric monoclinic space group C2/c: a = 15.018(1), b = 7.370(1), c = 21.189(1) Å, β = 110.17(1)°. Similar to 1, the Cu(II) cation in both compounds adopts the configuration of a distorted N2O2Cl2-octahedron generated by two N atoms and two O atoms belonging to the two 2-bzpy neutral ligands and two Cl anions in axial positions. Like in crystal packing of 1, in compound 2 the 2-bpzy ligands are stacked by the π-π interactions (centroid···centroid distance – 3.734 Å), giving a 2D supramolecular polymer. Weak C–H···Cl intermolecular hydrogen bonds make additional impact in stabilization of crystal structure. In conclusion, two mononuclear coordination compounds 1 and 2 were prepared and studied by the single-crystal X-ray diffraction method to elucidate the impact of different metal centers to crystal packing mode.