Scientific research over the last 5 years has confirmed that the health of the digestive tract and of the whole body depends on the microorganisms that colonize it [1-3]. Intestinal microflora is thought to be the mirror of the health of the host organism [4-6]. That is why the main goal of this research was to study the intestinal micro-organisms of children with different health status. According to the purpose, samples of intestinal (rectal) content from children of various ages and various health status of the digestive tract (sanogenic and pathological) were investigated. The genera Lactobacillus, as obligatory microorganisms, Eschericha - the optional ones, and Proteus - the putrefaction microorganisms, were considered. The numerical value of the intestinal microorganisms of the nominated genera, determined during the investigative process (at 7, 90 and 300 days after birth) is shown in Tab.1. The results are expressed in decimal logarithms. The results confirm a considerable difference between the quantitative indices of intestinal microbial agents in healthy and sick children. This is observed in group II of children with pathological condition of the digestive tract, where the obligatory Lactobacillus genus is numerically in minority (by 18.97; 19.43 and 22.71% compared to the children of the group I respectively at the age of 7, 90 and 300 days after birth). The difference was even greater for optional bacteria and rotting bacteria. It is to be noted that the quantitative indices of the genus Escherichia increased respectively by 43.98; 23.98 and 22.33%. The last indication demonstrates that Proteus genus was present only in children of group II (sick). Based on the obtained results, it can be stated that the microorganisms of the studied genera can serve as indicators of the state of health of the organism, because their quantitative indices respond promptly to the changes in children health status. 1.The sanogenic health state of digestive tube was characterized by: the numerical dominance of obligatory bacteria on the example of Lactobacillus genus; -minority of the facultative (Escherichia) and the lack of putrefaction (Proteus). 2. The pathological status of the digestive tract has shown inverse characteristics (the numerical decrease of the obligated microorganisms, the increased of facultative and the presence of putrefaction microflora).