In this experiment it has been studied the influence of ferment preparations Farmazyme 2575 and Des in mixed fodders composition on the use and digestion of nutritious substances at young pigs. The level of the ferment Farmazyme 2575 addition was determined in the scientific and economic experiments that were performed earlier. The ferment preparation Des was obtained and approved for the first time at the Institute of Microbiology of the ASM (Academy of Sciences of the Republic of Moldova). The data obtained in the physiological experiment showed, that in general the nutritious substances were used better by those pigs that received the addition of ferment preparation Des. A high protein digestion was also observed at the pigs of this group – 72,34% compared to 69,91% in the control group. The realized experiment showed that the studied ferment preparations had a favorable influence on the digestion, fodder use and young pigs growth; there were not essential differences between these ferments.