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SM ISO690:2012 LESNIC, Evelina, GHINDA, Serghei, USTIAN, Aurelia. Factorii clinici şi imunologici predictivi ai eşecului tratamentului tuberculozei pulmonare. In: Sănătate Publică, Economie şi Management în Medicină , 2014, nr. 4(55), pp. 36-41. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 4(55) / 2014 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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Pag. 36-41 | ||||||
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Moldova reports the biggest incidence of tuberculosis and the lowest succes treatment rate among European region countries. The most of patients, 90%, the antituberculosis treatment failure, is correlated with social risk factors (social, economical low status, social-epidemiological cathegorie of the population) and biological factors (young age, male sex, some physiological conditions, associated deseases). Clinical factors (extensive clinical radiological forms, chronic evolution, multiple immune disturbances), therapeutical factors (empiric treatment of multidrug-resistant tuberculosis, treatment interruptions, individualised treatment) and administrative factors (interrupted suppling, suboptimal treatment quality) prevales in regions with deffi ciencies in heath care delivery. Sthereotip, non-adherent to treatment behaviour of patients is associated with all related factors. Risk factors association values more evident than the severity of an one risk factor. Assessment of clinical and immunological risk factors for anti-tuberculosis treatment failure is important before initiation of the anti-tuberculosis treatment, for establishing of risk reduction measures and increasing succes rate. |
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Cuvinte-cheie tuberculosis, immune reactivity, treatment failure, risk factors |
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