This paper reflects the research carried out regarding the status in copper, zinc and iron depending to the intake of the mineral supplement `PMVAS` and establishing the correlation between the action of the food factor and the action of the low temperature of a moderate stress intensity on the organism of the calves in the early postnatal period. Thus, the paper presents the results of the separate action of the mineral premix `PMVAS` and its conjugate with the thermal factor on some indices of saline metabolism in calves in postnatal period carried out in order to correct the deficiency of trace elements and determine the parameters that can act beneficially on homeostasis, resistance and adaptive capacities of animals to the action of the environment. At the separate and combined application of the factors studied in dynamics (7, 30, 60, 90 days) on the organism of the calves were obtained representative data regarding the functional state of the organism demonstrating a moderate intensification of the metabolism of trace elements.