In this paper, the content of harmful and potentially harmful constituents (HPHCs) in conventional cigarette smoke and in the Tobacco Heating System 2.2 (THS 2.2) product, developed by Philip Morris International (PMI) and marketed under the brand name IQOS (I Quit Ordinary Smoking), as well as for conventional 3R4F cigarettes, was examined using statistical data obtained from studies of scientific papers published between 2015 and 2022. Based on the analysis of the results presented by independent and industry-sponsored studies, it was found that the harmful and potentially harmful constituents (HPHC) are not entirely eliminated from the HTP aerosol, so these products are still not without risks for the population. The data obtained for all analyzed chemicals, with the exception of the substance with order number 30, N-nitrosoanabasine, support the theory put out in this study, according to at least one group or multiple groups of independent experts. In other words, in each individual case, at least one group of independent experts attests that the information provided by the company’s experts about the concentrations of the analyzed compounds (at least for the maximum values obtained) in the aerosol stream emitted by an IQOS device is not diminished.

In this paper, the content of harmful and potentially harmful constituents (HPHCs) in conventional cigarette smoke and in the Tobacco Heating System 2.2 (THS 2.2) product, developed by Philip Morris International (PMI) and marketed under the brand name IQOS (I Quit Ordinary Smoking), as well as for conventional 3R4F cigarettes, was examined using statistical data obtained from studies of scientific papers published between 2015 and 2022. Based on the analysis of the results presented by independent and industry-sponsored studies, it was found that the harmful and potentially harmful constituents (HPHC) are not entirely eliminated from the HTP aerosol, so these products are still not without risks for the population. The data obtained for all analyzed chemicals, with the exception of the substance with order number 30, N-nitrosoanabasine, support the theory put out in this study, according to at least one group or multiple groups of independent experts. In other words, in each individual case, at least one group of independent experts attests that the information provided by the company’s experts about the concentrations of the analyzed compounds (at least for the maximum values obtained) in the aerosol stream emitted by an IQOS device is not diminished.