The paper summarizes the world and own experience using worm culture (earthworms) for utilization of various organic wastes, use of products worm cultivation (worm compost, biomass, worms and alarm pheromone) in a number of industries. Recognized features of physiological development and maintenance of worm culture, the stages and the basic conditions of industrial cultivation technology, the product features and their use. The bioconversion process of organic wastes is implemented in the Experimental Section of the Scientific and Practical Institute of Biotechnologies in Animal Husbandry and Veterinary Medicine. The studies conducted by several states, including Moldova, concluded that worm compost has a positive influence on crop productivity, reducing growth period, their resistance to unfavourable climatic conditions and common plant diseases. Worm cultivation opens up new perspectives and opportunities for introducing technology of obtaining the protein not only for feed purposes, but also in the food industry for the production ecological products. The results of research showed that the products obtained from biomass worms and alarm pheromone, can serve as raw material for the preparation of medicinal products used in medicine and in veterinary medicine for the control and prevention of various diseases. Technology of bioconversion of organic waste using worm culture is designed for landowners, farmers, ranchers, and agricultural enthusiasts, and others as an alternative method for the sustainable development of agriculture. The research conducted and analysis of results about the development of worm cultivation found that: worm cultivation is a branch that has the ability to solve stringent ecological problems existing in some sectors of the national economy, contributing to the development of sustainable agriculture and otained ecological agricultural productions, products obtained as a result of worm cultivation can be widely used in crop, livestock, human and veterinary medicine.