Introduction. If we are to refer to the term communication, it is necessary to mention that it is presented under various conceptual agglomerations, which includes a large number of domains. But in all fields the etymology of the word is based on the Latin term communication, meaning "to share". And if we were to refer to the pharmaceutical field, especially that of drug assistance, then the most appropriate field would be "Continuous exchange of messages, which generates the unity of views, and implicitly, of action, by harmonizing knowledge regarding goals, the ways and means to achieve them, by promoting the necessary skills, by the relative homogenization of the groups under affective (emotional, sentimental) and motivational aspects (opinions, interests, convictions, attitudes)". Aim of the study. Determining the content of the pharmacist's communication with the patient in the effective implementation of drug assistance to the population.Material and methods. The study was carried out through bibliographic analysis and questionnaires of 320 pharmacists, including graduate students of the Faculty of Pharmacy. With the following sample structure: 299 women, 21 men; 50 with a seniority of work up to 1 year, 76 with a seniority of work between 1-5 years, 74 with a seniority of work between 5-10 years, 120 with a seniority of work over 10 years; 105 occupying the positions of pharmacist-managers (branch chief), 215 pharmacists; 118 holders of the higher category, 60 of the I category, 37 of the II category and 105 without qualification category; Results and conclusions. For effective communication with the patient, the pharmacist must possess multiple communication skills, the most important being the ability to ask the patient to understand what he would like to achieve as a result of the conversation, to listen to what the patient wants in order to help him and to inform him about the options that would be advisable in his situation, to provide the patient with data, knowledge, arguments, examples, recommendations, capable of motivating him to accept and comply with the treatment. The result of the survey of pharmacists showed that they mostly apply verbal communication skills in their work 94.7%, para and non-verbal 44%. For an effective result of assistance with medicines, pharmacists consult on issues related to a healthy lifestyle and actions that fall under the notion of controlled self-medication (93.4%), correct administration and compliance with treatment - in all cases of dispensing medicines. At the same time, pharmacists mention that the sources available today are not sufficient for operative informational assurance about the entire range of medicines and about the patient, and some conditions in the pharmacy and activities they have to carry out constitute obstacles in the process of communication with the patient.