It was established that the trend of the general prevalence of the population in the Northern Development Region for 9 districts and the RDN (average value) is increasing. This fact is explained by the anthropogenic impact on the environment and, accordingly, on the general prevalence of the population. The prevalence with a constant trend is only in the municipality of Balti. The decreasing trend of prevalence in the RDN is established only in 2 districts. Based on the results obtained regarding the evaluation of the anthropogenic impact on the general prevalence of the population, it can be stated that the anthropogenic impact had an essential pressure on the environment, and the quality of the environment caused a negative effect on the health of the population, confirmed by the increasing trend of the population prevalence.