The tactics of management of pregnant females with Hodgkin lymphoma
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OLEINICOVA, Elena, CORCIMARU, Ion, IAKOVLEVA, Iraida, MUSTEAŢĂ, Larisa, ROBU, Maria, GLADÎŞ, Valentina, MUSTEAŢĂ, Vasile, BEJAN, Lilea. The tactics of management of pregnant females with Hodgkin lymphoma. In: Archives of the Balkan Medical Union Supliment, 2013, nr. S3(48), p. 76. ISSN 0041-6940.
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Archives of the Balkan Medical Union Supliment
Numărul S3(48) / 2013 / ISSN 0041-6940

The tactics of management of pregnant females with Hodgkin lymphoma


Pag. 76-76

Oleinicova Elena, Corcimaru Ion, Iakovleva Iraida, Musteaţă Larisa, Robu Maria, Gladîş Valentina, Musteaţă Vasile, Bejan Lilea
 
Institute of Oncology
 
 
Disponibil în IBN: 25 octombrie 2022


Rezumat

The aim of the current research was to study the tactics of management of pregnant females suffered of Hodgkin lymphoma (HL). Materials and methods: Five hundred and ten fertile women with HL had been followed up and treated at the Hematologic Center between 1965 and 2010. Two hundred and thirty-two pregnancies were supervised in 180 of these patients. The repeated pregnancies were registered in 52 patients. Results: Of 57 pregnant patients with the active disease, 39 were delivered of a child and other 18 underwent medical abortion. All these patients experienced the progression of HL during the pregnancy or thereafter. One hundred and seventy-five pregnancies occurred in 123 females with the remission of HL. The pregnancy was interrupted in 72 cases. One hundred and three pregnant women were delivered of a child. The progression of HL was observed in 27 (15%) patients. Of these 27 patients, 15 were delivered of a child and 12 underwent the medical abortion. The relapses occurred more frequently (89%) within the first three years of remission, and were observed significantly seldom (11%) at fourth and fifth year of remission. No relapses have occurred after 6 years of remission. Conclusions: In pregnant females with the active HL, or with the partial and short-term complete remission of HL the medical abortion is reasonable to be performed. The pregnancy may be maintained in cases of stable remission for 4, 5 and more years.

Cuvinte-cheie
pregnant females, Hodgkin lymphoma