In the current stage of anthropo-natural evolution of the arable chernozems of the Prut-Dniester space, the direction and intensity of typogenetic processes are determined by the qualitative-functional changes induced by agrogenesis, manifested in the interdetermined and interdependent degradation of pedofunctional system functionality [organic substances system-structural-aggregate system]. Their quantitative expression is the physical condition of the soils materialized in the physical (water, thermal, aeration) and pedofunctional (aerohydric, hydrothermal, biohydrothermal) regimes, which undergo significant changes, these being the main factor limiting the extended reproduction of the chernozemic process and natural fertility of arable chernozems. Their direct causes are the negative transformations of the structural-aggregate composition accompanied by the reduction of the total amount of accumulated organic matter and the degree of physical protection and its stability in the composition of the metastructural aggregates. The specified effects are exacerbated by climate change in the current climate trend in the region. Our research has shown that structural-aggregate degradation is manifested in: increase in aggregate content >5 mm; reduction of the content of optimal agronomic aggregates 5-1 mm; increasing the compaction of the aggregates 3-1 mm and reducing their porosity below 40%; reducing the porosity of aggregates 1-0.25 mm below 30%; reducing the aggregate hydrostability below 50% and increasing the slitization of the structure. The specified modifications lead to essential changes in the composition and functioning of the organic matter system: reduction of the total mass of bioenergetic resources and of the fraction of labile organic substances; increase of the share of humus in their composition; reducing the share of calcium humates and increasing the content of 'aggressive' fulvic acid fractions in the humic system; increasing the summary content of fulvic acids and reducing the ratio of Cah : Caf in the humus composition to values (1.5-1.2) uncharacteristic for chernozems. All this entails the intensification of the processes of physical degradation with the intensification of the processes of degradation of the ecosystem functions of chernozems, especially of the bioproductive and carbon-sequestration function. A quantitatively functional expression of them is the increase of the vulnerability of soils to climate change. In view of the concept of the priority role of the humification process in chernozemic pedogenesis, the technological solutions for unidirectional restoration of the direction and intensity of chernozemic processes presuppose the biologization of the anthropized chernozemic process. An element of perspective in this regard is the use of bio-organo-mineral preparations based on humic substances that ensure: the restoration of the composition of the soil biota; increasing the biological and enzymatic activity of the soil; intensifying the processes of fixing biological nitrogen and increasing the amount of biological nitrogen included in pedogenesis; intensifying the production processes in the „soil-plant” system and increasing the amount of bioenergetic resources included in pedogenesis; intensification of the processes of formation and accumulation of humus and organic and organo-mineral nutrients; improving soil structure, hydrophysical and trophic functions; expanded reproduction of the natural fertility of chernozemic processes.