Novel vic-dioximes: synthesis, structure characterization, and antimicrobial activity evaluation
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URECHE, Dumitru, BULHAK, Ion, CIOCARLAN, Alexandru, ROSHCA, Daniel, LUPAŞCU, Lucian, BOUROSH, Pavlina. Novel vic-dioximes: synthesis, structure characterization, and antimicrobial activity evaluation. In: Turkish Journal of Chemistry, 2021, nr. 6(45), pp. 1873-1881. ISSN 1300-0527. DOI: https://doi.org/10.3906/kim-2104-24
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Turkish Journal of Chemistry
Numărul 6(45) / 2021 / ISSN 1300-0527 /ISSNe 1303-6130

Novel vic-dioximes: synthesis, structure characterization, and antimicrobial activity evaluation

DOI:https://doi.org/10.3906/kim-2104-24

Pag. 1873-1881

Ureche Dumitru1, Bulhak Ion1, Ciocarlan Alexandru1, Roshca Daniel1, Lupaşcu Lucian1, Bourosh Pavlina12
 
1 Institute of Chemistry,
2 Institute of Applied Physics
 
 
Disponibil în IBN: 21 ianuarie 2022


Rezumat

The vic-dioximes are compounds with various industrial uses and scientific applications. Many coordination compounds have been synthesized based on vic-dioximes. This study presents the synthesis and full characterization of two vic-dioximes based on dichloroglyoxime, p-aminobenzoic acid, and p-aminotoluene. Their structures were proved by IR, 1H, 13C and 15N NMR spectral analysis, and single crystal X-ray diffraction. One of the reported vic-dioximes, bis(di-p-aminotoluene)glyoxime mono-p-aminotoluene trihydrate showed good to moderate antimicrobial activity against both nonpathogenic gram-positive and gram-negative bacteria (Bacillus subtilis and Pseudomonas fluorescens), phytopathogenic (Xanthomonas campestris, Erwinia amylovora, E. carotovora) and the fungi (Candida utilis and Saccharomyces cerevisiae) at MIC – 70–150 μg/mL.

Cuvinte-cheie
Antibacterial activity, Antifungal activity, Spectral analysis, Vic-dioxime, X-ray diffraction

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