European Union is the most powerful integration block from the world. Since 1957, countries from the old continent understood that they will succeed in their further development only by working together, and this is when the story of the European Economic Community begins. But is looks like after 60 years, something has changed. Therefore, United Kingdom decided that it is no more convenient for them to be part of the EU, and, through a referendum, decided to exit from it. In the present article, the author tried to analyze the possible consequences of this event both UK and EU, and also, for the Republic of Moldova. Even if it is not yet part of the Union, this may affect the European course of our country. Therefore, the proposed aim of the research is to find out what may occur in the near future.