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SM ISO690:2012 GAVRILIU, Liana Cătălina, MURARIU, Carmen, POTOP, Vladimir, SPĂTARU, Radu Iulian. Characteristics of the pediatric patients diagnosed with SARS-CoV-2 infection in a Romanian children's hospital: A retrospective study. In: PeerJ, 2021, nr. 9, pp. 1-19. ISSN 2167-8359. DOI: https://doi.org/10.7717/peerj.11560 |
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PeerJ | |
Numărul 9 / 2021 / ISSN 2167-8359 | |
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DOI:https://doi.org/10.7717/peerj.11560 | |
Pag. 1-19 | |
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Background: To date, information on COVID-19 pediatric patients is still sparse. We aimed to highlight the epidemiological and clinical data regarding SARS-CoV-2 infection in children and adolescents to improve the understanding of the disease in this age group and inform physicians during the ongoing COVID-19 pandemic. Methods: We conducted a retrospective, observational study in "Marie Curie" Emergency Children's Hospital from Bucharest, Romania. We analyzed clinical and epidemiological characteristics of the patients confirmed with SARS-CoV-2 infection, between April 1, 2020-October 31, 2020. Results: A total of 172 patients aged 0-18 years were included, 79 (45.93%) female and 93 (54.07%) male patients. 28 (16.28%) patients had co-morbidities (more often identified in asymptomatic group; p < 0.0001). 47 (27.32%) had exposure to an identified source. 30 (17.44%) patients were asymptomatic; 142 (85.56%) had mild or moderate disease. The most frequent symptoms were: Pyrexia (78.87%), digestive symptoms (50%), cough (40.14%). Chest X-ray was performed in 50 patients and it was abnormal in half of them, all being symptomatic. About 2/3 of the evaluated patients had normal leukocytes. The most common hematological change was lymphopenia; monocytes tended to be higher in symptomatic patients. About 40% of the patients were admitted; none required admission to ICU. No significant differences were found between symptomatic and asymptomatic patients regarding gender, age distribution, and exposure to a source. Conclusions: All the patients had asymptomatic, mild or moderate disease. Patients with comorbidities, classically considered high risk patients, presented the same pattern of disease. |
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Cuvinte-cheie Clinical and epidemiological characteristics, COVID-19, Laboratory and radiological characteristics, Symptomatic and asymptomatic patients, symptoms |
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