In a nuclear world some states decide to enter into military alliances and increase their defensive strength, and the American Missile Defence System is one of the ways. However, the United States and Russia, who together hold the largest part of global strategic nuclear arsenal, are fully involved in a broader dialogue on disarmament and non-proliferation of weapons of mass destruction. The Agreement START (Strate- gic Arms Reduction Treaty) III signed recently in Prague or negotiations on the Irani- an nuclear file is part of this dialogue. In this context, the Moldovan national interest requires maintenance of military neutrality, with a dignified and, most importantly, neutral on the continental strategic repositioning.