Articolul precedent |
Articolul urmator |
485 11 |
Ultima descărcare din IBN: 2024-03-24 14:59 |
SM ISO690:2012 BURAC, Mihaela, FRIPTU, Valentin, PETROVICI, Virgil, COROLCOVA, Natalia, PROFIRE, Liliana. Abordarea clinică a infertilității primare: datarea histologică a endometrului. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 579. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 579-579 | ||||||
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Background. The role of the endometrium in the pathogenesis of infertility cannot be denied, as it represents the fundamental structure in implantation. The association of secondary infertility with chronic inflammatory process is widely studied, but few studies elucidate it’s condition in primary infertility. Objective of the study. Assess the histological structure of the endometrium in patients with primary infertility and in fertile patients. Material and Methods. A prospective, cohort study was performed that included 96 patients divided into two groups: L1 - the study group with 48 patients with primary infertility and L0 - the control group that included 48 fertile patients. Endometrial tissue was collected by Pipelle biopsy. The results of the study were statistically analyzed using SPSS 20 and Microsoft Excel. Results. The histological study of the endometrium in the group of patients with primary infertility presents: inflammatory changes of the endometrial tissue in 79.2% (38) vs. group of fertile patients 31.3% (15), χ2 = 22,238; p<0.001; endometrial stromal edema L1 85.4% (41) vs L0 54.2% (26), χ2= 12,099; p = 0.002; endometrial stroma fibrosis L1 6.3% (2) vs L0 0% (0), χ2 = 3.097; p = 0.07; periglandular inflammatory changes L1 60.4% (29) vs L0 6.3% (3), χ2 = 9.478; p = 0.002; perivascular inflammatory changes L1 58.3% (28) vs L0 50% (24), χ2 = 5.061; p = 0.024; plasma cells L1 25.0% (12) vs L0 8.3% (4), χ2 = 4,800; p = 0.028. Conclusion. The endometrium of patients suffering from primary infertility express inflammatory changes and especially characteristic for the chronic inflammatory process. |
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Cuvinte-cheie endometrium, infertility, microbiome, Noyes criteria, endometru, infertilitate, microbiom, criteriile Noyes |
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