The study includes research on the status of representative ecosystems of the Basin of the Prut River: Landscape Reserve (LR) - Suta de Movile, Geology and Palaeontology Nature Monument (GPNM) – Gorge Duruitoarea and Natural Forest Reserve (NFR) - Saptebani. The study assessed the overall environmental condition, identified and assessed the sources and the level of pollution of environmental components, registered and described the species of flora and fauna, identified the rare species which are protected nationally and internationally. Based on the investigation parameters, it was concluded that the investigated objects are in good ecological state and serve as a favourable habitat for many rare species of flora and fauna, with national and international protection status. Water quality of the Duruitoarea and the Ciuguret rivers, which cross NFR Saptebani and GPNM Gorge Duruitoarea correspond to class II of surface water quality. The impact from local and transboundary sources of pollution, calculated based on the amounts of pollutants emitted, is insignificant. The inseparable interdependence between abiotic and biotic factors of ecosystems comes to convince about the need to protect landscapes as a whole, integrally, both geological and hydrological elements and flora and fauna species, a requirement stipulated by European Landscape Convention, Florence, 2000. The presented material serves as scientific a support to argue the protection category of investigated objects.