The 21st century competences focus on higher-order thinking, problem solving, effective communication, self-directed and collaborative learning – required by a global, digital society. They can be clustered as ways of thinking, ways of working, tools for working, and living in the world [1, p.14]. Living in the world (personal area), ways of working (social area) and ways of thinking (learning to learn) are all linked to the fourth area (tools for working: information and ICT literacy, as parts of digital competence). Furthermore, development of key competence learning to learn should not be considered separately from the digital competence. The aim of European Framework for Personal, Social and Learning to Learn Key Competence used as reference in the article is to establish a shared understanding, and a common language on the „Personal, Social and Learning to Learn” competences and is utilized to guide some of transversal skills development through school curriculum in secondary education. The key competence learning to learn requires integration in the study of all school subjects as a transversal key competence and transdisciplinary dimension; currently it is not intentionally and programmed integrated, the focus being on developing skills specific to the subject studied in the school curriculum