Articolul precedent |
Articolul urmator |
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SM ISO690:2012 ARICU, Aculina, KUCHKOVA, Kaleria, SECARA-KUȘNIR, Elena, BARBA, Alic, DRAGALIN, Ion, UNGUR, Nikon. Synthesis of some new homodrimane sesquiterpenoids with 1,3,4- oxadiazole fragment. In: Romanian Chemistry Conference, 2-5 octombrie 2018, Călimăneşti-Căciulata, Vâlcea . Călimăneşti-Căciulata, Vâlcea, România: Centrul de Cercetare Oltchim, 2018, Ediția a XXXV-a, p. 187. |
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Romanian Chemistry Conference Ediția a XXXV-a, 2018 |
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Conferința "Romanian Chemistry Conference" Călimăneşti-Căciulata, Vâlcea , Romania, 2-5 octombrie 2018 | ||||||
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Pag. 187-187 | ||||||
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Teza |
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Many drimane sesquiterpenoids exhibit various types of biological activity [1]. In continuation of our investigation on the synthesis of nitrogen-containing drimane and homodrimanesesquiterpenoids [2, 3], we herein describe the synthesis of 5-(Δ8,9- bicyclohomofarnesenyl)-1,3,4-oxadiazol-2(3H)-one (7) and 2-amino-5-(Δ8,9-bicyclohomo-farnesenyl)-1,3,4-oxadiazol (8) from commercially available norambreinolide (1) according to the scheme: Reagents and conditions: a) DMSO, P2O5, CH2Cl2, 0°C, 10 min, 20°C, 45 min; Et3N, 0°C, 10 min, 20°C, 45 |
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