| Conţinutul numărului revistei |
| Articolul precedent |
| Articolul urmator |
 228 0 |
 SM ISO690:2012MAKAEV, Fliur, RUSU, Ghenadie, POGREBNOI, Serghei, GUDIMA, Alexandru, STYNGACH, Evgenia, VLAD, Liudmila, SHVETS, Nathaly, KANDEMIRLI, Fatma, DIMOGLO, Anatholy, REYNOLDS, Robert C.. Synthesis of novel 5-aryl-2-thio-1,3,4-oxadiazoles and the study of their structure-anti-mycobacterial activities. In: Bioorganic and Medicinal Chemistry, 2005, vol. 13, pp. 4842-4850. ISSN 0968-0896. DOI: https://doi.org/10.1016/j.bmc.2005.05.011 |
| EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
  Bioorganic and Medicinal Chemistry |
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| Volumul 13 / 2005 / ISSN 0968-0896 /ISSNe 1464-3391 | |
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| DOI:https://doi.org/10.1016/j.bmc.2005.05.011 | |
| Pag. 4842-4850 | |
| Rezumat | |
The preparation of novel 5-aryl-2-thio-1,3,4-oxadiazoles 4a-41 and the computer-aided study of their in vitro anti-tubercular activity against Mycobacterium tuberculosis H37Rv (ATCC 27294) are reported. The average accuracy of the electronic-topological method and neural network methods applied to the activity prediction in leave-one-out cross validation is 80%. |
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| Cuvinte-cheie 5-Aryl-2-thio-1, 3, 4-oxadiazoles, Anti-tubercular activity, Electronic-topological method, Neural network method, Structure-activity relationships |
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