The purpose of master's thesis on the topic: "Nitroglycerin and acetylsalicylic acid a preventive remedy of prolonged action in case of heart attack" was to elaborate a formulation of a new prophylactic agent of prolonged action for myocardial infarction based on nitroglycerin and acetylsalicylic acid. The proposed drug will be effective for the relief and systematic prevention of angina attacks, which can develop into myocardial infarction, and also as a rehabilitation treatment after myocardial infarction. Acetylsalicylic acid was obtained in laboratory conditions by two methods. The active and auxiliary components of the potential drug were subjected to chemical and pharmaceutical analyzes. After fabrication the dosage form, it was also subject to quality control, in accordance with the requirements of the current regulatory and technical documentation. The proofs of the prolonged effect of the dosage form are presented.