Generating Diversity in Natural Product Scaffolds. Synthesis of ent-Kauranic Derivatives Functionalized with Triazole Fragments
Închide
Articolul precedent
Articolul urmator
325 1
Ultima descărcare din IBN:
2021-06-10 13:45
SM ISO690:2012
GÎRBU, Vladilena; GRINCO, Marina; UNGUR, Nicon; KULCIŢKI, Veaceslav; RENAUD, Philippe. Generating Diversity in Natural Product Scaffolds. Synthesis of ent-Kauranic Derivatives Functionalized with Triazole Fragments. In: Medical Plants – present and perspectives Dedicated to the 60-year celebration of the „Stejarul” Biological Research Centre. Ediția a 12-a, 6-9 septembrie 2016, Piatra Neamț. Piatra Neamț, România: NIRDBS/„Stejarul“ Biological Research Centre, 2016, pp. 144-145.
EXPORT metadate:
Google Scholar
Crossref
CERIF

DataCite
Dublin Core
Medical Plants – present and perspectives
Ediția a 12-a, 2016
Simpozionul "Medical Plants – present and perspectives"
Piatra Neamț, Romania, 6-9 septembrie 2016

Generating Diversity in Natural Product Scaffolds. Synthesis of ent-Kauranic Derivatives Functionalized with Triazole Fragments


Pag. 144-145

Gîrbu Vladilena12, Grinco Marina1, Ungur Nicon12, Kulciţki Veaceslav12, Renaud Philippe3
 
1 Institute of Chemistry of the Academy of Sciences of Moldova,
2 University of the Academy of Sciences of Moldova,
3 University of Bern
 
Disponibil în IBN: 6 august 2020


Rezumat

The current work presents the first results on the application of the radical hydroazidation
methodology for the functionalization of ent-kaurenic derivatives which represent an important family
of natural diterpenoids with relevant biological activities. Following conversion of obtained azide to
different triazoles containing hybrids was acheived via a click-chemistry procedure involving several
alkynes.



Cuvinte-cheie
Hydroazidation, click reaction, radical chemistry, diterpenes