In the Republic of Moldova, regardless the limited area, regional climate change represents one of the major threats for sustainable development and is one of the biggest environmental problems, with negative consequences for the national economy. Displacement function analysis of the climate rules distribution which is characterizing mean annual temperature at different times in the Republic of Moldova shows that the last decade of the twentieth century (1989-1999) was the warmest decade of the century. At the same time, the first decade (2000-2012) of XXI century is the warmest decade of instrumental observations series (1887-2013). Measurement of the extreme values modification in the Moldova’s climate evolution indicates that absolute maximum of temperatures and deficit (excess) of precipitation have a regular manifestation on the last period (2000-2012).