The article is dedicated to the legal aspects of bilateral water relations of Moldova and Ukraine on their joint Dniester River demonstrating that only the following international legislation on transboundary waters could help both riparians to save the river for future generations. Current situation with domination of hydrower as dominating used is unacceptable from the sustainable development view. The newly created Dniester River Commission could be a tool to establish a dialogue and a platform for wise decision making. The success could be only reached in case of following the best international standards due to climate change consequences for the region, which provoke droughts etc.