Sunflower is the most important oil producing plant in our country. The high production capacity and high seed oil content ensures large oil yields per hectare – the basic target of sunflower breeding and cultivation. The sunflower breeding work at the Research Institute of Field Crops “Selectia” is done towards direction of creation of precocious hybrids with a vegetation period of 95105 days, seeds yield of 2.5-3.5 t/ha, fat content of 48-50%; as well as creation of middletardily hybrids with a vegetation period of 105-120 days, seeds yield of 3.5-4.2 t/ha, fat content of 50-53%. Precocity is achieved by repeated individual selection or by hybridization with early forms and varieties. Middle-tardily and tardily biotypes due to a longer vegetation period provide higher yields than early forms. As initial material to create inbred lines were used early and middle-tardily varietiespopulation which possesses valuable genes for breeding of lines from the world collection (A.V.Anascenco). Researches on breeding have been directed towards creation of commercial hybrids based on cytoplasmic androsterility and pollen fertility restoration. The main methods for creating the original material are inbreeding and recurrent selection, use of the heterosis effect and creation of experimental hybrids. The sunflower hybrids breeding system depends on the quality of the parental forms of inbred lines. After 4-5 generations of inbreeding and recurrent selection, successful descendants are included in cross-over schemes of topckross type and diagrams to determine combinatorial capacity. The best lines based on general and specific combination capacity are included in the collection of workstation lines. Annually, about 2500 descendants of different imbriding degrees are studied and experimented in the nursery of inbred lines. Simultaneously, over 300 hybrid combinations are studied. They are selected high-productive forms resistant to disease with a large number of seeds a mass of in pseudanthium, 1000 seeds 50-60 g, fat content of 50-53%, low shells percentage (22-25%) with elastic and small diameter. As a result of the research, 14 new lines of superior combining qualities with precious genes have been created. On their basis, a number of sunflower hybrids have been selected. The best ones were sent for testing in the State Commission. Currently, 6 hybrids created at RIFC “Selectia” are registered in the Catalog of Plant Varieties of the Republic of Moldova. For testing in 2018, to the State Commission for testing were sent two hybrids – HS-1021 (early) and HS-1017 (middle-long), which during 3 years of research in the comparative fields showed superiority of seed production and oil contend compare to witnesses.