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SM ISO690:2012 COREŢCHI, Liuba. Particularităţile efectelor imunologice ale genomului uman în condiţii de stres radiogen
. In: Sănătate Publică, Economie şi Management în Medicină , 2010, nr. 2(31), pp. 37-42. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 2(31) / 2010 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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Pag. 37-42 | ||||||
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In this paper are presented immunological effects particularities and individual dosimeter control results of the occupationally exposed workers (OEW) employed in the radiological therapy and radiological diagnostic, to ionizing radiations. The peripheral blood lymphocytes immunological
phenotypization has been made by using monoclonal antibodies (OOO „Sorbent”, Moscow, Rusia). The number of CD3 , CD4 , CD8 , CD16 , CD19 T-lymphocytes and CDHLA DR has been determined by utilising „FACS-COUNT”flow cytometry and „LOMO” luminescent microscope. Length of service (seniority) in the radiogen stress conditions, age and individual accumulated doses of the OEW were taken into consideration during the results’ analysis. The termoluminiscent (TLD) dosimeters have been used in the process of individual dosimeter monitoring of the OEW. A data base was created in Access and afterwards exported to Microsoft Excel,
the latter being used for descriptive statistic. The results demonstrated the general dysfunction of the OEW immunological system, which manifested itself through the diminution, balance or co-expression of the superficial determinants responsible with immunity system. The individual doses of the investigated OEW were within admissible levels according to Fundamental Norms of Radiation Protection standards.
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Cuvinte-cheie Ionizing radiations, immunological effects, occupationally exposed workers, monoclonal antibodies |
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