Due to the strong anthropogenic pressure on the territory of the Republic of Moldova the entomofauna is depleted. However, the goal is to create in the human modified environment not only a highly productive, but also a relatively stable agrocenosis. Leaf beetles (Chrysomelidae) belong to its important components due to their ubiquity and the large number of species. It should be noted that the value of leaf beetles is wider than that of simple pests. However, if the approach is applied to their evaluation as to the components of biocenoses, the role of beetles appear to be somewhat different. Of course, some of the most important pests belong to this group of insects. It is sufficient to recall such mass pests like Leptinotarsa decemlineata Say, Oulema spp., Altica quercetorum Foudr. or the fact that the decorative Ulmus spp. in Chisinau were heavily damaged by Xanthogaleruca luteola Mull. In general, however, the leaf beetles biodiversity must be preserved. After all, the vast majority of the representatives from these families are not pests. In addition, several species of leaf beetles are used in biological control of weeds. Leaf beetles are a link in the trophic chains of the insect fauna, which is important for the development of an integrated plant protection, as well as to support the biodiversity of entire regional entomofauna. On this basis, it is required to optimize the entomofauna within the agricultural landscapes, taking into account the entire spectrum of trophic links of both leaf beetles and other insects. So, bearing in mind that the representatives of these groups of beetles that live on unusual plants may suffer losses at their detection, their breeding potential will drop in comparison with the inhabitants of conventional plants. To avoid this limiting factor, i.e. the territorial fragmentation of fodder plants, it is advisable to provide a sort of „bridges”, which may be in the form of a network of polyfunctional forest strips and their loops with certain plants composition. After all, the biodiversity of fauna of leaf beetles, as well as the insect fauna in general (of which their stability largely depends), is due to the diversity, sufficiency and availability of its food resources. This implies the importance of preserving the natural habitat places with the full range of their plants. The general premise of biodiversity of the insect fauna, including fam. Chrysomelidae, is a “mosaic” of vegetation landscapes, including the presence of habitats of different quality - “oasis” with wild plants and forest areas. At the same time it is one of important factors of creating relatively stable cenoses, which would be able to self-regulate as far as possible along with the suppression of mass species.