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 873 19 |
| Ultima descărcare din IBN: 2022-10-26 08:58 |
| Căutarea după subiecte similare conform CZU |
| 615.225.2.035.1 (1) |
| Medicamentele potrivit acţiunii lor principale (395) |
 SM ISO690:2012GHICAVÎI, Victor, BACHINSKY, N.G., PODGURSKY, L. A., ŢURCAN, Lucia, CHIANU, Marin. Selection of antihypertensive drugs from the perspective of clinical pharmacology. In: Moldovan Medical Journal, 2018, nr. 1(61), pp. 18-23. ISSN 2537-6373. DOI: https://doi.org/10.5281/zenodo.1186184 |
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| Moldovan Medical Journal | ||||||
| Numărul 1(61) / 2018 / ISSN 2537-6373 /ISSNe 2537-6381 | ||||||
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| DOI:https://doi.org/10.5281/zenodo.1186184 | ||||||
| CZU: 615.225.2.035.1 | ||||||
| Pag. 18-23 | ||||||
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Background: The rational use of medicines remains one of the most important directions of public health, especially in socio-medical diseases, including arterial hypertension. Material and methods: The study involved 28 cardiologists and 84 internists who, based on a set of questionnaires, expressed their opinion on ambulatory treatment of patients with arterial hypertension. Also 21 internists, 6 cardiologists and 6 obstetrician-gynecologists expressed their opinion on treatment of pregnancy-induced hypertension. Results: Cardiologists and internists recommended angiotensin-converting-enzyme inhibitors (ACE inhibitors) in 28% of cases, diuretics – in 23% of cases, beta-blockers (BB) – in 20, 4% of cases, calcium channel blockers (CCB) – in 13.7% of cases, angiotensin receptor blockers (ARB) – in 13.6% of cases for ambulatory treatment of patients with arterial hypertension. The antihypertensive drugs from other pharmacological groups (with central action, alpha-blockers, arteriodilators, sympatholytics, etc.) were prescribed in only 1.3% of patients. On treatment of hypertension in pregnancy showed that all physicians – 100% recommended as first-line agent for treatment of hypertension during pregnancy centrally acting antihypertensive drug Methyldopa. For second-line treatment they recommended CCB – in 36.36% of cases, alpha-adrenoblockers – in 24.24% of cases, BB – in 21.21% of cases, diuretics – in 12.12% of cases and 3% for ACE inhibitors and ARB. For treatment pre-eclampsia and eclampsia seizures in 84.85% of cases is recommended Magnesium sulfate and 15.15% mention labetalol, hydralazine and sodium nitroprusside. Conclusions: ACE inhibitors, diuretics, BAB, CCB and ARB have been first-line drugs in the arterial hypertension (AHT) treatment. For treatment of pregnancy-induced hypertension physicians recommended centrally acting antihypertensive drug Methyldopa. For second-line treatment they recommended calcium channel blockers (CCB), alpha-adrenoblockers, beta-blockers (BB) and diuretics. As third-choice in treatment of severe hypertension in preeclampsia are selected direct vasodilators as hydralazine, labetalol, sodium nitroprusside, and the most widely used in preeclampsia and eclampsia remains magnesium sulfate. |
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| Cuvinte-cheie arterial hypertension, antihypertensive drugs, angiotensin-converting-enzyme inhibitors |
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Dublin Core Export
<?xml version='1.0' encoding='utf-8'?> <oai_dc:dc xmlns:dc='http://purl.org/dc/elements/1.1/' xmlns:oai_dc='http://www.openarchives.org/OAI/2.0/oai_dc/' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xsi:schemaLocation='http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd'> <dc:creator>Ghicavâi, V.I.</dc:creator> <dc:creator>Bacinschi, N.G.</dc:creator> <dc:creator>Podgurschi, L.</dc:creator> <dc:creator>Ţurcan, L.M.</dc:creator> <dc:creator>Chianu, M.</dc:creator> <dc:date>2018-03-30</dc:date> <dc:description xml:lang='en'><p><strong>Background: </strong>The rational use of medicines remains one of the most important directions of public health, especially in socio-medical diseases, including arterial hypertension. <strong>Material and methods</strong>: The study involved 28 cardiologists and 84 internists who, based on a set of questionnaires, expressed their opinion on ambulatory treatment of patients with arterial hypertension. Also 21 internists, 6 cardiologists and 6 obstetrician-gynecologists expressed their opinion on treatment of pregnancy-induced hypertension. <strong>Results: </strong>Cardiologists and internists recommended angiotensin-converting-enzyme inhibitors (ACE inhibitors) in 28% of cases, diuretics – in 23% of cases, beta-blockers (BB) – in 20, 4% of cases, calcium channel blockers (CCB) – in 13.7% of cases, angiotensin receptor blockers (ARB) – in 13.6% of cases for ambulatory treatment of patients with arterial hypertension. The antihypertensive drugs from other pharmacological groups (with central action, alpha-blockers, arteriodilators, sympatholytics, etc.) were prescribed in only 1.3% of patients. On treatment of hypertension in pregnancy showed that all physicians – 100% recommended as first-line agent for treatment of hypertension during pregnancy centrally acting antihypertensive drug Methyldopa. For second-line treatment they recommended CCB – in 36.36% of cases, alpha-adrenoblockers – in 24.24% of cases, BB – in 21.21% of cases, diuretics – in 12.12% of cases and 3% for ACE inhibitors and ARB. For treatment pre-eclampsia and eclampsia seizures in 84.85% of cases is recommended Magnesium sulfate and 15.15% mention labetalol, hydralazine and sodium nitroprusside. <strong>Conclusions: </strong>ACE inhibitors, diuretics, BAB, CCB and ARB have been first-line drugs in the arterial hypertension (AHT) treatment. For treatment of pregnancy-induced hypertension physicians recommended centrally acting antihypertensive drug Methyldopa. For second-line treatment they recommended calcium channel blockers (CCB), alpha-adrenoblockers, beta-blockers (BB) and diuretics. As third-choice in treatment of severe hypertension in preeclampsia are selected direct vasodilators as hydralazine, labetalol, sodium nitroprusside, and the most widely used in preeclampsia and eclampsia remains magnesium sulfate.</p></dc:description> <dc:identifier>10.5281/zenodo.1186184</dc:identifier> <dc:source>Moldovan Medical Journal 61 (1) 18-23</dc:source> <dc:subject>arterial hypertension</dc:subject> <dc:subject>antihypertensive drugs</dc:subject> <dc:subject>angiotensin-converting-enzyme inhibitors</dc:subject> <dc:title>Selection of antihypertensive drugs from the perspective of clinical pharmacology</dc:title> <dc:type>info:eu-repo/semantics/article</dc:type> </oai_dc:dc>
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