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SM ISO690:2012 PELTEC, Angela, HOTINEANU, Adrian, HOTINEANU, Vladimir, BRAŞOVEANU, Vlad, DUMBRAVA, Vlada-Tatiana, TARAN, Natalia, IVANCOV, Grigore. Steatoza hepatică nonalcoolică și transplantul hepatic: controverse, rezultate și progrese. In: Sănătate Publică, Economie şi Management în Medicină , 2014, nr. 5(56), pp. 149-152. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | |||
Numărul 5(56) / 2014 / ISSN 1729-8687 /ISSNe 2587-3873 | |||
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Pag. 149-152 | |||
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Nonalcoholic fatty liver disease affects a substantial proportion of the general population worldwide. This high prevalence of nonalcoholic fatty liver disease has important consequences in the donor selection process for liver transplantation, and in the post transplant period given the high recurrence rate of disease. De novo NAFLD can also occur in the allograft of patients transplanted for nonNAFLD liver disease. Predictors for NAFLD post-transplant recurrence include obesity, hyperlipidemia and diabetes as well as steroid dose after liver transplantation. A polymorphism in PNPLA3 that mediates triglyceride hydrolysis is linked to pre-transplant risk of obesity and has also been linked to post transplant NAFLD risk. This paper reviews the implications of NAFLD in both the pre- and post-liver transplantation setting |
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Cuvinte-cheie nonalcoholic fatty liver disease, liver transplant |
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