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<creators>
<creator>
<creatorName>Apostol, T.</creatorName>
<affiliation>Universitatea de Medicină şi Farmacie „Carol Davila“, România</affiliation>
</creator>
<creator>
<creatorName>Socea, L.</creatorName>
<affiliation>Universitatea de Medicină şi Farmacie „Carol Davila“, România</affiliation>
</creator>
<creator>
<creatorName>Barbuceanu, S.</creatorName>
<affiliation>Universitatea de Medicină şi Farmacie „Carol Davila“, România</affiliation>
</creator>
<creator>
<creatorName>Saramet, I.</creatorName>
<affiliation>Universitatea de Medicină şi Farmacie „Carol Davila“, România</affiliation>
</creator>
<creator>
<creatorName>Olaru, O.</creatorName>
<affiliation>Universitatea de Medicină şi Farmacie „Carol Davila“, România</affiliation>
</creator>
<creator>
<creatorName>Draghici, C.</creatorName>
<affiliation>Centrul de Chimie Organica "Costin D. Nenitescu", România</affiliation>
</creator>
</creators>
<titles>
<title xml:lang='en'>Synthesis, characterization and phytobiological evaluation of new 2-[4-(4-bromophenylsulfonyl)phenyl]-
4-methyloxazol-5(4h)-one and some new 5-aryl-2-[4-(4-bromophenylsulfonyl)phenyl]-4-methyloxazoles
</title>
</titles>
<publisher>Instrumentul Bibliometric National</publisher>
<publicationYear>2014</publicationYear>
<relatedIdentifier relatedIdentifierType='ISSN' relationType='IsPartOf'>1812-5077</relatedIdentifier>
<subjects>
<subject schemeURI='http://udcdata.info/' subjectScheme='UDC'>615.322</subject>
</subjects>
<dates>
<date dateType='Issued'>2014-12-11</date>
</dates>
<resourceType resourceTypeGeneral='Text'>Journal article</resourceType>
<descriptions>
<description xml:lang='en' descriptionType='Abstract'>Heterocyclic compounds containing 1,3-oxazol-5(4H)-one and 1,3-oxazole ring are important targets in synthetic and medicinal chemistry, because of their applications as potentially active compounds. Thus, some 1,3-oxazol-5(4H)-ones have been reported to present antimicrobial and antitumor activity. 1,3-Oxazoles are frequent substructures in various biologically active compounds used in therapeutics as anti-inflammatory (e.g. Oxaprozin, Romazarit, Ditazol, Isamoxole), analgesic (e.g. Oxaprozin), antibacterial, antifungal (e.g. Sulfamoxole, Sulfaguanole), muscle relaxant (e.g. Azumolene) drugs. Therefore, there is considerable interest to synthesize new 1,3-oxazole5(4H)-ones and 1,3-oxazoles which contain 4-(4-bromophenylsulfonyl) phenyl moiety in 2 position with a hope to obtain potent biologically active compounds. The plant growth regulatory effects of the new compounds were examined. </description>
</descriptions>
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