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SM ISO690:2012 POPESCU, Victor, CORCIMARU, Ion, BUTOVSCAIA, Cristina, ZUIEVA, Anastasiia, BURUIANA, Sanda, SIMIONICĂ, Eugeniu. Prevalenţele unor profiluri metilice ale promotorului genei la persoane sănătoase şi printre pacienţii cu leucemii acute
. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2009, nr. 3(10), pp. 236-243. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 3(10) / 2009 / ISSN 1857-1719 | ||||||
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Pag. 236-243 | ||||||
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In this study we have obtained some methylic profiles in DNA extracted from venous
blood of healthy persons and patients with acute leukemias. Some methylic profiles could act as
molecular markers in the acute leukemias monitoring (prognosis, differencial-epigenetic
diagnosis and personalized treatment). We have also obtained preliminary results on some
methylic profiles prevalences in DNA of healthy persons and patients with acute leukemias. The conclusion consists of MM methylic profile of p15gene promoter which can be used as
candidate molecular marker with low-risk for the examined person who can be affected with
acute leukemia immediately after the blood sample collection. |
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