reported as a frequent complication among critically ill patients admitted with COVID-19, associated with high mortality and recognized as an indicator of multiple organ dysfunction and disease severity. Material and methods. A retrospective study was conducted, including patients with confirmed COVID-19 infection admitted to Republican Clinical Hospital «Timofei Mosneaga» between June 01, 2020 and August 31, 2020. Obtained data were compared between patients with AKI and without AKI. Results. Of the 81 patients included in the study, 49 (60,49%) were male and 32 (39,50%) were female. The median age was 61 years (interquartile range - 55-60). Twenty patients (24,69%) had acute kidney injury, of whom 4 patients (20%) required renal replacement therapy. Of the 20 patients, 5(25%) developed stage I AKI, 7 (35%) developed stage II and 8 (40%) stage III. Risk factors for the development of AKI during hospitalization were: assisted breathing and vasopressor support. Of the twenty patients with AKI and urinalysis, 65% had proteinuria, 45% had hematuria. Mortality rates were significantly higher in patients with AKI (90% versus 36,06%). Conclusions. Patients with COVID-19 have a high incidence of acute kidney injury. At the same time, AKI significantly increases the mortality of patients admitted to intensive care units. Of all patients with AKI, only 10% survived with recovery of renal function until discharge.