Introduction. Kidney cancer is the 14th most common cancer in the world. The incidence of malignant renal tumors in the Republic of Moldova, between 2014-2022 was 9.3 patients per 100,000/ year. Partial nephrectomy (PN) is considered gold standard of care in patients with cT1 renal tumor masses. Aim. Analyze the surgical and oncological outcomes in patients with renal tumors and obtaining the optimal strategies for patients with localized renal cancer. Material and methods. A retrospective pilot study carried out on 86 patients with kidney tumor who underwent open PN during 2014-2023. Results. During the study were performed 920 interventions on patients with renal tumor, of which 9.34% of cases were performed PN. Increased incidence was at age group 40-60 years, with female’s prevalence. PN without warm ischemia (WIT) was performed in 60 patients, while with WIT in 26 patients, without impact on renal function after surgery. RCC >7cm was present in 66.2% of cases with localization at the upper renal poles (29%), lower (37%) and at midkidney (34%). WIT was performed in 26 patients (14.8±4.2minute). Intraoperative bleeding was present in 100% in PN without WIT (29.8±13ml). The ratio of histological types of renal malignant tumors was 57% of cases, the highest incidence was RCC (66%) in men (83%). Conclusion. PN with WIT is valuable when we assume that intraoperative complications and a difficult reconstruction of the kidneys that can occur due to the complexity of the tumor ensuring a low risk of intraoperative bleeding.