Health-related quality of life and the impact of antimicrobial resistance
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FERDOHLEB, Alina, CROITORU, Cătălina, CIOBANU, Elena, SPINEI, Larisa. Health-related quality of life and the impact of antimicrobial resistance. In: Individual, family, society – contemporary challenges, Ed. 5, 4-5 octombrie 2023, București. București, România: 2023, Ediția 5, p. 31.
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Individual, family, society – contemporary challenges
Ediția 5, 2023
Conferința "Individual, family, society – contemporary challenges"
5, București, Romania, 4-5 octombrie 2023

Health-related quality of life and the impact of antimicrobial resistance

CZU: 616.9:615.281.9.015.8+614.2

Pag. 31-31

Ferdohleb Alina, Croitoru Cătălina, Ciobanu Elena, Spinei Larisa
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
 
Disponibil în IBN: 11 martie 2024


Rezumat

Objectives. Some microbes develop resistance to drugs that were previously able to fight them and now pose an increasing threat to global health, a process called antimicrobial resistance. Ambient temperature can impact the spread and growth of bacteria, potentially contributing to the development of antimicrobial resistance and increasing the risk of bacterial infections. Material and Methods. A cross-sectional study was carried out, using the questionnaire "Assessment of knowledge, Attitudes and Practices of health workers regarding antimicrobial resistance in European LMIC" developed in the framework of the project "Phage treatment and wetland technology as an intervention strategy to prevent dissemination" of antibiotic resistance in surface waters; 66 people were surveyed. The questionnaire included 80 questions, of which 7 were analysed and excluded. The instrument was tested, obtaining a Cronbach alpha coefficient value = 0.93. The research methodology was approved by the Ethics Committee of the Ministry of Health (1245/26.01.2022) and the Nicolae Testemițanu SUMPh of the RM (7/09.01.2022). Results. To assess the attitudes of healthcare workers towards two crucial phenomena antimicrobial resistance and climate change - they had to indicate which one was more salient by answering two trap questions. As a result, more respondents indicated that antimicrobial resistance was more important. Less than half (48.5%) of the medical workers answered affirmatively to the question of whether there is a connection between climate change and multi-resistant pathogens. Of all healthcare workers, 30.3% were convinced and 57.6% believed that climate change has the potential to increase the burden and morbidity caused by antimicrobial-resistant microorganisms. 22.7% of respondents were convinced that the incidence of bacterial infections is associated with the increase in ambient temperature, and 37.9% considered this association likely. Regarding the statement that the prevalence and range of antimicrobial-resistant Vibrio species increases due to ocean warming as the climate warms, 21.2% of respondents strongly agreed, and 63.6% believed it was likely. About the fact that Vibrio species become more resistant to antimicrobials due to microplastics and lead to outbreaks of antimicrobial-resistant cholera and necrotizing fasciitis, 16.7% of respondents were convinced, and 60.6% believed it was likely. Scientific studies have shown that high temperatures can increase a person's irritability and reduce critical thinking. Therefore, the opinion of medical workers was analyzed to determine if heatwaves could affect the prescription of antimicrobial drugs. Only 18.2% of respondents mentioned that such an effect could be registered, while 34.8% were convinced that there would be no such effects, 39.4% did not know, and 7.6% refused to answer. As ambient temperatures rise, horizontal gene transfer increases, which is a major mechanism for acquiring antimicrobial resistance. Only 15.2% of health workers were convinced of this, and a high proportion, 57.7%, considered it likely. Conclusions. High ambient temperatures generally increase bacterial growth rates. Climate change is a social justice issue, and its unmitigated progress will disproportionately affect the health and well-being of people in low- and middle-income countries around the globe.

Cuvinte-cheie
antimicrobial resistance, climate change, heat stress, human health, low and middle income countries